Similar build to other posted high-score here.Edit
Went with shield build, but used grab potions instead of grab shields, since the combo makes it easy to select all shields anyway. The ability to clear potions meant being able to get maximum shields with the combo, AND meant full life refills lategame, which made a big difference. I could have kept going, but it was an unlucky run, with only 19 blunting total.
~280 spike damage
Max pierce, armor durability, and lifesteal.